WRIM PUBLICATIONS 2022

Alafo, C., Martí-Soler, H., Máquina, M., Malheia, A., Aswat, A.S., Koekemoer, L.L., Colborn, J., Lobo, N.F., Tatarsky, A., Williams, Y.A., Marrenjo, D., Cuamba, N., Rabinovich, R., Alonso, P., Aide, P., Saúte, F. & Paaijmans, K.P. 2022. To spray or target mosquitoes another way: focused entomological intelligence guides the implementation of indoor residual spraying in southern Mozambique. Malaria Journal 21:215. https://doi.org/10.1186/s12936-022-04233-3.

Arendse, L.B., Murithi, J.M., Qahash, T., Pasaje, C.F.A., Godoy, L., Gibhard, L., Ghidelli-Disse, S., Drewes, G., Bantscheff, M., Lafuente-Monasterio, M.J., Fienberg, S., Wambua, L., Gachuhi, S., Coertzen, D., van der Watt, M., Reader, J., Aswat, A.S., Erlank, E., Venter, N., Mittal, N.,  Luth, M.R., Ottilie, S.,  Winzeler, E.A., Koekemoer, L.L., Birkholtz, L.M., Niles, J.C., Llinás, M., Fidock, D.A. & Chibale, K. 2022. The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and lifecycle stages. Science Translational Medicine 14 (667) e-print. https://www.science.org/doi/abs/10.1126/scitranslmed.abo7219 .

Bradbury, R.S., Sapp, S.G.H., Potters, I., Mathison, B.A., Frean, J., Mewara, A., Sheorey, H., Tamarozzi, F., Couturier, M.R., Chiodini, P., Pritt, B. 2022. Where Have All the Diagnostic Morphological Parasitologists Gone? Journal of Clinical Microbiology, 60(11):e0098622.  https://10.1128/jcm.00986-22.

Brooke, B.D. 2022. Malaria vector surveillance and control in an elimination setting in South Africa. Tropical Medicine & Infectious Disease 7, 391. https://doi.org/10.3390/tropicalmed7110391.

Coetzee, B.W.T., Gaston, K.J., Koekemoer, L.L., Kruger, T., Riddin, M.A. & Smit, I.P.J. 2022. Artificial light as a modulator of mosquito-borne disease risk. Frontiers in Ecology and Evolution  9: 768090. https://doi.org/10.3389/fevo.2021.768090.

Coetzee, M. 2022. Literature review of the systematics, biology and role in malaria transmission of species in the Afrotropical Anopheles subgenus Anopheles (Diptera: Culicidae). Zootaxa 5133(2): 182-200. https://doi.org/10.11646/zootaxa.5133.2.2.

De Boni, L., Mall, S., Msimang, V., de Voux, A., Rossouw, J. & Frean, J. 2022. Exposure of South African abattoir workers to Coxiella burnetii. Tropical Medicine and Infectious Diseases 7:28. https://doi.org/10.3390/tropicalmed7020028. 

Etang, J., Mandeng, S.E., Nwane, P., Awono-Ambene, H.P., Bigoga, J.D., Ekoko, W.E., Binyang, A.J., Piameu, M., Mbakop, L.R., Mvondo, N., Tabue, R., Mimpfoundi, R., Toto, J.C., Kleinschmidt, I., Knox ,T.B., Mnzava, A.P., Donnelly, M.J. & Fondjo, E. 2022. Patterns of Kdr-L995F allele emergence alongside detoxifying enzymes associated with deltamethrin resistance in Anopheles gambiae s.l. from North Cameroon. Pathogens 11:253. https://doi.org/110.3390/pathogens11020253. 

Erlank, E., Venter, N. & Koekemoer, L.L. 2022. Standard membrane feeding assay for detection of Plasmodium falciparum infection in Anopheles mosquito vectors. Journal of Visualized Experiments: JoVE 183: e63546. https://doi.org/10.3791/63546. 

Fernández Montoya, L., Máquina, M., Martí-Soler, H., Sherrard-Smith, E., Alafo, C., Opiyo, M., Comiche, K., Galatas, B., Huijben, S., Koekemoer, L.L., Oliver, S.V., Maartens, F., Marrenjo, D., Cuamba, N., Aide, P., Saúte, F., & Paaijmans, K. P. 2022. The realized efficacy of indoor residual spraying campaigns falls quickly below the recommended WHO threshold when coverage, pace of spraying and residual efficacy on different wall types are considered. PloS One, 17(10), e0272655. https://doi.org/10.1371/journal.pone.0272655.

Fernández Montoya, L., Martí-Soler, H., Máquina, M., Comiche, K., Cuamba, I., Alafo, C., Koekemoer, L.L., Sherrard-Smith, E., Bassat, Q., Galatas, B., Aide, P., Cuamba, N., Jotamo, D., Saúte, F., & Paaijmans, K.P. 2022. The mosquito vectors that sustained malaria transmission during the Magude project despite the combined deployment of indoor residual spraying, insecticide-treated nets and mass-drug administration. PloS One, 17(9), e0271427. https://doi.org/10.1371/journal.pone.0271427.

Flegg, J.A., Humphreys, G.S., Montanez, B., Strickland, T., Jacone-Meza, Z.J, Barnes, K.I., Raman, J., Guerin, P.J., Sibley, C.H. & Otienoburu, S.D. 2022. Spatiotemporal spread of Plasmodium falciparum mutations for resistance to sulfadoxine-pyrimethamine across Africa, 1990-2020. PLoS Computational Biology. 18(8): e1010317. https://doi.org/10.1371/journal.pcbi.1010317. 

Gebhardt, M.E., Krizek, R.S., Coetzee, M., Koekemoer, L.L., Dahan-Moss, Y., Mbewe, D., Lupiya, J.S., Muleba, M., Stevenson, J.C., Moss, W.J. & Norris, D.E. 2022. Expanded geographic distribution and host preference of Anopheles gibbinsi in northern Zambia. Malaria Journal 21: 211. https://doi.org/10.1186/s12936-022-04231-5.  

Ippolito, M.M., Gebhardt, M.E., Ferriss, E., Schue, J.L., Kobayashi, T., Chaponda, M., Kabuya, J-B., Muleba, M., Mburu, M., Matoba, J., Musonda, M., Katowa, B., Lubinda, M., Hamapumbu, H., Simubali, L., Mudenda, T., Wesolowski, A., Shields, T.M., Hackman, A., Shiff, C., Coetzee, M., Koekemoer, L., Munyati, S., Gwanzura, L., Mutambu, S., Stevenson, J.C., Thuma, P.E., Norris, D.E., Bailey, J.A., Juliano, J.J., Chongwe, G., Mulenga, M., Simulundu, E., Mharakurwa, S., Agre, P.C. & Moss, W.J. 2022. Scientific Findings of the Southern and Central Africa International Centers of Excellence for Malaria Research: Ten Years of Malaria Control Impact Assessments in Hypo-, Meso- and Holoendemic Transmission Zones in Zambia and Zimbabwe. American Journal of Tropical Medicine & Hygiene 107(Suppl 4): 55-67. https://doi.org/10.4269/ajtmh.21-1287.

Jeanrenaud, A.C.S.N., Brooke, B.D., Oliver, S.V. 2022. Characterisation of the epigenetic architecture of the major malaria vector Anopheles arabiensis (Diptera: Culicidae) after treatment with epigenetic modulators and heavy metals. Acta Tropica 226: 106259. https://doi.org/10.1016/j.actatropica.2021.106259.

Kagoro, F.M., Allen, E., Mabuza, A., Workman, L., Magagula, R., Kok, G., Davies, C., Malatje, G., Guérin, P.J., Dhorda, M., Maude, R.J., Raman, J. &, Barnes, K.I. 2022. Making data map-worthy-enhancing routine malaria data to support surveillance and mapping of Plasmodium falciparum anti-malarial resistance in a pre-elimination sub-Saharan African setting: a molecular and spatiotemporal epidemiology study. Malaria Journal 21:207. https://doi.org/10.1186/s12936-022-04224-4.

Kahamba, N.F., Finda, M., Ngowo, H.S., Msugupakulya, B.J., Baldini, F., Koekemoer, L.L., Ferguson, H.M. & Okumu FO. 2022. Using ecological observations to improve malaria control in areas where Anopheles funestus is the dominant vector. Malaria Journal 21:158. https://doi.org/10.1186/s12936-022-04198-3.

Kumala, J., Koekemoer, L.L., Coetzee, M. & Mzilahowa, T. 2022. Intensity of insecticide resistance in the major malaria vector Anopheles funestus from Chikwawa, rural southern Malawi. Parasites & Vectors 15: 220. https://doi.org/10.1186/s13071-022-05299-3.

Labuschagne, J., Frean, J., Parbhoo, K., Mutyaba, D., Pillay, T., Boughan, S., Nkala, H. Disseminated Human Subarachnoid Coenurosis. 2022. Tropical Medicine and Infectious Disease, 7: 405. https://doi.org/10.3390/tropicalmed7120405.

Maharaj, S., Ekoka, E., Erlank, E., Nardini, L., Reader, J., Birkholtz, L.M. & Koekemoer, L.L. 2022. The ecdysone receptor regulates several key physiological factors in Anopheles funestus. Malaria Journal 21: 97. https://doi.org/10.1186/s12936-022-04123-8.

Markus, M.B. 2022. Helminthiasis, eosinophils, COVID-19 and vaccination. Southern African Journal of Infectious Diseases 37(1): a423. https://doi.org/10.4102/sajid.v37i1.423.

Markus, M.B. 2022. Theoretical origin of genetically homologous Plasmodium vivax malarial recurrences. Southern African Journal of Infectious Diseases 37(1): a369. https://doi.org/10.4102/sajid.v37i1.369.

Markus, M.B. 2022. How does primaquine prevent Plasmodium vivax malarial recurrences? Trends in Parasitology 38 (11): 924–925. https://doi.org/10.1016/j.pt.2022.09.006.

Mosha, J.F., Kulkarni, M.A., Lukole, E., Matowo, N.S., Pitt, C., Messenger, L.A., Mallya, E., Jumanne, M., Aziz, T., Kaaya, R., Shirima, B.A., Isaya, G., Taljaard, M., Martin, J., Hashim, R., Thickstun, C., Manjurano, A., Kleinschmidt, I., Mosha, F.W., Rowland, M. & Protopopoff, N. 2022. Effectiveness and cost-effectiveness against malaria of three types of dual-active-ingredient long-lasting insecticidal nets (LLINs) compared with pyrethroid-only LLINs in Tanzania: a four-arm, cluster-randomised trial. The Lancet 399(10331):1227-1241. https://doi.org/10.1016/S0140-6736(21)02499-5.

Munhenga, G., Oliver, S.V., Lobb, L.N., Mazarire, T.T., Sekgele, W., Mashatola, T., Mabaso, N., Dlamini,D.M., Zulu, M., Molestane, F., Letinic, B.D., Zawada, J., Burke, A., Dahan-Moss, Y., Matamba, A., Kaiser, M., Brooke, B.D. 2022 Malaria risk and receptivity: Continuing development of insecticide resistance in the major malaria vector Anopheles arabiensis in northern KwaZulu-Natal, South Africa. South African Journal of Science 118(3/4): #11755. http://dx.doi.org/10.17159/sajs.2022/11755.

Ntuku, H., Smith-Gueye, C., Scott, V., Njau, J., Whittemore, B., Zelman, B., Tambo, M., Prach, L.M., Wu, L., Schrubbe, L., Kang Dufour, M.S., Mwilima, A., Uusiku, P., Sturrock, H., Bennett, A., Smith, J., Kleinschmidt, I., Mumbengegwi, D., Gosling, R. & Hsiang, M. 2022. Cost and cost effectiveness of reactive case detection (RACD), reactive focal mass drug administration (rfMDA) and reactive focal vector control (RAVC) to reduce malaria in the low endemic setting of Namibia: an analysis alongside a 2×2 factorial design cluster randomised controlled trial. BMJ Open 12:e049050. http://dx.doi.org/10.1136/bmjopen-2021-049050. 

Oliver, S.V., Lyons, C.L., Brooke, B.D. 2022. The effect of blood feeding on insecticide resistance intensity and adult longevity in the major malaria vector Anopheles funestus (Diptera: Culicidae). Scientific Reports 12(1): 3877. https://doi/org/10.1038/s41598-022-07798-w.

Pinda, P.G.,  Msaky, D.S., Muyaga, L.L., Mshani, I.H., Njalambaha, R.M.,  Kihonda, J., Bwanaly, H.,  Ngowo, H.S., Kaindoa, E.W.,  Koekemoer, L.L. & Okumu, F.O. 2022. Correlations between age, distance from aquatic habitats and pyrethroid resistance status of field populations of the malaria vector, Anopheles funestus in south-eastern Tanzania. Malaria Journal 21:365. https://doi.org/10.1186/s12936-022-04389-y .

Reddy, D.L., van den Berg, E., Grayson, W., Mphahlele, M. & Frean, J. 2022. Clinical improvement of disseminated acanthamoeba infection in a patient with advanced HIV using a non-miltefosine-based treatment regimen in a low-resource setting. Tropical Medicine and Infectious Diseases 7:24. https://doi.org/10.3390/tropicalmed7020024.

Rants'o, T. A., van Greunen, D.G., van der Westhuizen, C. J., Riley, D.L., Panayides, J.L., Koekemoer, L.L., & van Zyl, R.L. 2022. The in silico and in vitro analysis of donepezil derivatives for Anopheles acetylcholinesterase inhibition. PloS One, 17(11), e0277363. https://doi.org/10.1371/journal.pone.0277363 .

Rants’o, T.A., Koekemoer, L.L., Panayides, J.-L., & van Zyl, R.L. 2022. Potential of Essential Oil-Based Anticholinesterase Insecticides against Anopheles Vectors: A Review. Molecules  27: 7026. https://doi.org/10.3390/molecules27207026.

Rosenthal, P.J., Björkman, A., Dhorda, M., Djimde, A., Dondorp, A.M., Gaye, O., Guerin, P.J., Juma, E., Kwiatkowski, D.P., Merson, L., Ntoumi, F., Price, R.N., Raman, J., Roos, D.S., Ter Kuile, F., Tinto, H., Tomko, S.S., White, N.J. & Barnes, K.I. 2022. Cooperation in Countering Artemisinin Resistance in Africa: Learning from COVID-19. American Journal of Tropical Medicine & Hygiene, 106:1568–1570.  https://doi.org/10.4269/ajtmh.22-0148.

Seanego, T.D., Chavalala, H.E., Henning, H.H., de Koning, C.B., Hoppe, H.C., Ojo, K.K., Rousseau, A.L. 2022. 7H-Pyrrolo[2,3-d]pyrimidine-4-amines as potential inhibitors of Plasmodium falciparum calcium-dependent protein kinases. ChemMedChem, 17: e202200421. https://doi.org/10.1002/cmdc.202200421.

Singh, A., Allam, M., Kwenda, S., Khumalo, Z.T.H., Ismail, A., Oliver, S.V.  2022. The dynamic gut microbiota of zoophilic members of the Anopheles gambiae complex (Diptera: Culicidae). Scientific Reports 12(1): 1495. https://doi/org/10.1038/s41598-022-05437-y 

Singh A, Patel NF, Allam M, Chan WY, Mohale T, Ismail A, Oliver SV. 2022. Marked Effects of Larval Salt Exposure on the Life History and Gut Microbiota of the Malaria Vector Anopheles merus (Diptera: Culicidae). Insects. 13(12):1165. https://doi.org/10.3390/insects13121165.

Somandi, K., Seanego, T.D., Dlamini (née Molatsane), T., Maree, M., de Koning,  C.B., Vanichtanankul, J., Rattanajak, R., Saeyang, T., Yuthavong, Y., Kamchonwongpaisan, S., Rousseau A.L. 2022. Molecular docking studies, synthesis and biological evaluation of substituted pyrimidine-2,4-diamines as inhibitors of Plasmodium falciparum dihydrofolate reductase. ChemMedChem, 17:e202200418. https://doi.org/10.1002/cmdc.202200418.

Tootla, H.D., Eley, B.S., Enslin, J.M.N., Frean, J.A., Hlela, C., Kilborn, T.N., Moodley, B., Peer, S., Singh, S., Nuttall, J.J.C. Balamuthia mandrillaris granulomatous amoebic encephalitis: The first African experience. 2022. Journal of the Pediatric Infectious Diseases Society, 11(12): 578-581.  https://doi.org/10.1093/jpids/piac096.

Stepniewska, K., Humphreys, G.S., Gonçalves, B.P., Craig, E., Gosling, R., Guerin, P.J., Price, R.N., Barnes, K.I., Raman, J., Smit, M.R., D'Alessandro, U., Stone, W.J.R., Bjorkman, A., Samuels, A.M., Arroyo-Arroyo, M.I., Bastiaens, G.J.H., Brown, J.M., Dicko, A., El-Sayed, B.B., Elzaki, S.E., Eziefula A.C., Kariuki, S., Kwambai, T.K., Maestre, A.E., Martensson, A., Mosha, D., Mwaiswelo, R.O., Ngasala, B.E., Okebe, J., Roh, M.E., Sawa, P., Tiono, A.B., Chen, I., Drakeley, C.J. & Bousema, T. 2022. Efficacy of single-dose primaquine with artemisinin combination therapy on Plasmodium falciparum gametocytes and transmission: An individual patient Meta-Analysis. Journal of Infectious Diseases 225(7):1215-1226. https://doi/org/10.1093/infdis/jiaa498.

Stepniewska, K., Allen, E.N., Humphreys, G.S., Poirot, E., Craig, E., Kennon, K., Yilma, D., Bosema, T., Guerin, P.J., White, N.J., Price, R.N., Raman, J.,  Martensson, A., Mwaiswelo, R.O., Bancone, G., Bastiaens, G.J.H., Bjorkman, A., Brown, J.M., D'Alessandro, U., Dicko, A.A., El-Sayed, B., Elzaki, S.E., Eziefula A.C., Gonçalves, B.P.,  Hamid, M.M.A., Kaneko, A., Kariuki, S., Khan, W., Kwamba, T.K., Ley, B., Ngasala, B.E., Nosten, F., Okebe, J., Samuels, A.M., Smit, M.R., Stone, W.J.R., Sutanto, I., Ter Kuile, F., Tine, R.C., Tiono, A.B., Drakeley, C.J., Gosling, R., Stergachis, A., Barnes, K.I. & Chen, I. 2022. Safety of single-dose primaquine as a Plasmodium falciparum gametocytocide: a systematic refiew and meta-analysis of individual patient data. BMC Medicine 20:350.  https://doi.org/10.1186/s12916-022-02504-z 

Wesolowski, A., Ippolito, M.M., Gebhardt, M.E., Ferriss, E., Schue, J.L., Kobayashi, T., Chaponda, M., Kabuya, J-B., Muleba, M., Mburu, M., Matoba, J., Musonda, M., Katowa, B., Lubinda, M., Hamapumbu, H., Simubali, L., Mudenda, T., Shields, T.M., Hackman, A., Shiff, C., Coetzee, M., Koekemoer, L., Munyati, S., Gwanzura, L., Mutambu, S., Stevenson, J.C., Thuma, P.E., Norris, D.E., Bailey, J.A., Juliano, J.J., Chongwe, G., Mulenga, M., Simulundu, E., Mharakurwa, S., Agre, P.C. & Moss, W.J. 2022. Policy Implications of the Southern and Central Africa International Center of Excellence for Malaria Research: Ten Years of Malaria Control Impact Assessments in Hypo-, Meso-, and Holoendemic Transmission Zones in Zambia and Zimbabwe. American Journal of Tropical Medicine & Hygiene 107(Suppl 4): 68-74. https://doi.org/10.4269/ajtmh.21-1288.

Wu, L., Hsiang, M.S., Prach, L.M., Schrubbe, L., Ntuku, H., Dufour, M.K., Whittemore, B., Scott, V., Yala, J., Roberts, K.W., Patterson, C., Biggs, J., Hall, T., Tetteh, K.K.A., Gueye, C.S., Greenhouse, B., Bennett, A., Smith, J.L., Katokele, S., Uusiku, P., Mumbengegwi, D., Gosling, R., Drakeley, C. & Kleinschmidt, I. Serological evaluation of the effectiveness of reactive focal mass drug administration and reactive vector control to reduce malaria transmission in Zambezi Region, Namibia: Results from a secondary analysis of a cluster randomised trial. EclinicalMedicine 44: 101272. https://doi.org/10.1016/j.eclinm.2022.101272.

Zengenene, M.P., Munhenga, G., Okumu, F. & Koekemoer, L.L. 2022. Effect of larval density and additional anchoring surface on the life-history traits of a laboratory colonised Anopheles funestus strain. Medical and Veterinary Entomology 36: 168-175. https://doi.org/10.1111/mve.12563.